{"id":5408,"date":"2025-01-15T03:29:01","date_gmt":"2025-01-15T03:29:01","guid":{"rendered":"http:\/\/loopitm.org.cn\/?page_id=5408"},"modified":"2025-07-04T08:29:12","modified_gmt":"2025-07-04T08:29:12","slug":"%e5%91%a8%e5%9c%8b%e8%b1%aa","status":"publish","type":"page","link":"http:\/\/loopitm.org.cn\/en\/%e5%91%a8%e5%9c%8b%e8%b1%aa\/","title":{"rendered":"Karl Zhou"},"content":{"rendered":"
\n\t\t\t\t\t\t
\n\t\t\t\t\t\t\t
<\/div>\n\t\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t
\n\t\t\t\tHome<\/a>\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t
\n\t\t\t\t\t
\n\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Asian Academy of Anti-Aging Research and Translational Medicine\uff08AAAR\uff09<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t\t

Karl Zhou<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t
  • Vice President, The Loop Institute of Innovative Translational Medicine<\/li>
  • Vice President, Asian Academy of Anti-aging Research and Translational Medicine (AAAR)<\/li>
  • Former Chief Medical Officer, Kintor Pharmaceutical<\/li>
  • Former Medical manager, UnitedHealth Group<\/li>
  • Former Medical Director, Pfizer<\/li>
  • Former Medical Manager, Schering-Plough (MSD)<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t
    \n\t\t\t\t\t
    -<\/h5>\t\t\t\t<\/div>\n\t\t\t\t
    \n\t\t\t\t\t\t\t\t\t

    Karl Zhou is a U.S.-trained medical oncologist and clinical scientist with over 30 years of experience in oncology translational medical research and drug development. Dr. Zhou has held various leadership positions with increasing responsibilities at Schering-Plough, Pfizer and i3 (an affiliate of United Healthcare).\nWith great interest of clinical innovation (from 0 to 1) and focusing on patient centric research, Dr. Zhou has made significant contributions to the development of innovative cancer therapies, including Yervoy (ipilimumab)-the first FDA-approved CTLA-4 checkpoint inhibitor for melanoma in 2011, followed by advancements in PD-1 inhibitors (such as pembrolizumab and nivolumab) and oncolytic virus therapies (e.g., CVA-21). His expertise spans antibody therapies, targeted tyrosine kinase inhibitors (TKIs), and immuno-oncology, across multiple tumor types.<\/p>

    He has published extensively on clinical trial data involving innovative drugs, methodologies and technologies. Dr. Zhou completed his postdoctoral and oncology clinical fellowship training at Dana-Farber Cancer Institute and Harvard Medical School under Dr. Emil Frei III, an internationally renowned clinician and a pioneer of combination chemotherapy.<\/p>

    Dr. Zhou earned his Ph.D. in Molecular Pharmacology and cancer research from Baylor College of Medicine and graduated from Shanghai First Medical College. His areas of expertise include solid tumors such as melanoma, non-small cell lung cancer (NSCLC), breast cancer, prostate cancer, and liver cancer. He also initiated several Chinese clinical research collaboration groups, including CSCO, SHOT, and ChinaHep.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

    \n\t\t\t\t\t
    \n\t\t
    \n\t\t
    \n\t\t\t\t
    \n\t\t\t\t\t\t\t
    \n\t\t\t
    \n\t\t\t<\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t
    \n\t\t\t\t\t
    Clinical trials and research can be likened to both art and science, owing to their inherent rigor and complexity. They embody the lengthy and arduous nature of scientific inquiry, while also being imbued with the beauty and elegance of artistic creation. The thinking, experience, and intuition of a seasoned clinician can often shape or change the course of a study's development and ultimate outcome.<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
    \n\t\t\t\t\t\t\t
    \n\t\t\t\n\t\t\t\t\t\t\t
    \n\t\t\t\tKarl Zhou\t\t\t\t<\/h6>\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
    \n\t\t\t\t\t
    \n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

    Home \u4e9e\u6d32\u6297\u8870\u8001\u53ca\u8f49\u5316\u91ab\u5b78\u7814\u7a76\u9662\uff08AAAR\uff09 \u5468\u570b\u8c6a \u6cb3\u5957\u6df1\u6e2f\u79d1\u6280\u5275\u65b0\u8f49\u5316\u91ab\u5b78\u7814\u7a76\u9662\u526f\u9662\u9577\uff08\u81e8\u5e8a\u91ab\u5b78\u53ca\u8a3b\u518a […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-5408","page","type-page","status-publish","hentry"],"rankMath":{"parentDomain":"loopitm.org.cn","noFollowDomains":["facebook.com","youtube.com","Instagram.com","TikTok.com","Twitter.com","LinkedIn.com","Pinterest.com","Snapchat.com","wa.me"],"noFollowExcludeDomains":[],"noFollowExternalLinks":true,"featuredImageNotice":"The featured image should be at least 200 by 200 pixels to be picked up by Facebook and other social media sites.","pluginReviewed":false,"postSettings":{"linkSuggestions":false,"useFocusKeyword":false},"frontEndScore":false,"postName":"%e5%91%a8%e5%9c%8b%e8%b1%aa","permalinkFormat":"http:\/\/loopitm.org.cn\/en\/%pagename%\/","showLockModifiedDate":true,"assessor":{"focusKeywordLink":"http:\/\/loopitm.org.cn\/wp-admin\/edit.php?focus_keyword=%focus_keyword%&post_type=%post_type%","hasTOCPlugin":true,"primaryTaxonomy":false,"serpData":{"title":"","description":"","focusKeywords":"","pillarContent":false,"canonicalUrl":"","breadcrumbTitle":"","advancedRobots":{"max-snippet":"-1","max-video-preview":"-1","max-image-preview":"large"},"facebookTitle":"","facebookDescription":"","facebookImage":"","facebookImageID":"","facebookHasOverlay":false,"facebookImageOverlay":"","facebookAuthor":"","twitterCardType":"","twitterUseFacebook":true,"twitterTitle":"","twitterDescription":"","twitterImage":"","twitterImageID":"","twitterHasOverlay":false,"twitterImageOverlay":"","twitterPlayerUrl":"","twitterPlayerSize":"","twitterPlayerStream":"","twitterPlayerStreamCtype":"","twitterAppDescription":"","twitterAppIphoneName":"","twitterAppIphoneID":"","twitterAppIphoneUrl":"","twitterAppIpadName":"","twitterAppIpadID":"","twitterAppIpadUrl":"","twitterAppGoogleplayName":"","twitterAppGoogleplayID":"","twitterAppGoogleplayUrl":"","twitterAppCountry":"","robots":{"index":true},"twitterAuthor":"username","primaryTerm":0,"authorName":"aaar","titleTemplate":"%title% - %sitename%","descriptionTemplate":"%excerpt%","showScoreFrontend":true,"lockModifiedDate":false},"powerWords":["a cut above","absolute","absolutely","absolutely lowest","absurd","abuse","accurate","accuse","achieve","actionable","adaptable","adequate","admit","adorable","advantage","advice","affordable","aggravate","aggressive","agitated","agonizing","agony","alarmed","alarming","alienated","aligned","alive","all-inclusive","alluring","always","amazing","amp","animated","annihilate","announcing","anonymous","antagonistic","anxious","apocalypse","appalled","approved","approving","argumentative","armageddon","arrogant","ass kicking","assault","assured","astonishing","astounded","astounding","at ease","atrocious","attack","attractive","audacity","authentic","authoritative","authority","avoid","aware","awe-inspiring","awesome","awkward","backbone","backdoor","backed","backlash","backstabbing","badass","balanced","banned","bargain","barrage","basic","battle","beaming","beat down","beating","beautiful","beauty","begging","behind the scenes","belief","belong","best","best-selling","better","beware","big","billion","black market","blacklisted","blast","blessed","blinded","blissful","blood","bloodbath","bloodcurdling","bloody","blunder","blushing","bold","bomb","bona","bona fide","bonanza","bonus","bootleg","bottom line","bountiful","brave","bravery","brazen","break","breaking","breakthrough","breathtaking","bright","brilliant","broke","brutal","budget","buffoon","bullshit","bully","bumbling","buy","cadaver","calm","cancel anytime","capable","captivate","captivating","carefree","case study","cash","cataclysmic","catapult","catastrophe","caution","censored","centered","certain","certainly","certified","challenge","charming","cheap","cheat","cheat-sheet","cheer","cheerful","child-like","clarity","classified","clear","clueless","collapse","colorful","colossal","comfortable","compare","competitive","complete","completely","completeness","comprehensive","compromise","compulsive","concealed","conclusive","condemning","condescending","confess","confession","confessions","confident","confidential","conquer","conscientious","constructive","content","contrary","controlling","controversial","convenient","convert","cool","cooperative","copy","corpse","corrupt","corrupting","courage","courageous","cover-up","covert","coward","cowardly","crammed","crave","crazy","create","creative","cringeworthy","cripple","crisis","critical","crooked","crush","crushing","damaging","danger","dangerous","daring","dazzling","dead","deadline","deadly","death","decadent","deceived","deceptive","deep","defiance","definitely","definitive","defying","dejected","delicious","delight","delighted","delightful","delirious","delivered","demoralizing","deplorable","depraved","desire","desperate","despicable","destiny","destroy","detailed","devastating","devoted","diagnosed","direct","dirty","disadvantages","disastrous","discount","discover","disdainful","disempowered","disgusted","disgusting","dishonest","disillusioned","disoriented","distracted","distraught","distressed","distrustful","divulge","document","dollar","dominate","doomed","double","doubtful","download","dreadful","dreamy","drive","drowning","dumb","dynamic","eager","earnest","easily","easy","economical","ecstatic","edge","effective","efficient","effortless","elated","eliminate","elite","embarrass","embarrassed","embarrassing","emergency","emerging","emphasize","empowered","enchant","encouraged","endorsed","energetic","energy","enormous","enraged","enthusiastic","envy","epic","epidemic","essential","ethical","euphoric","evil","exactly","exasperated","excellent","excited","excitement","exciting","exclusive","exclusivity","excruciating","exhilarated","expensive","expert","explode","exploit","explosive","exposed","exquisite","extra","extraordinary","extremely","exuberant","eye-opening","fail","fail-proof","failure","faith","famous","fantasy","fascinating","fatigued","faux","faux pas","fearless","feast","feeble","festive","fide","fierce","fight","final","fine","fired","first","first ever","flirt","fluid","focus","focused","fool","fooled","foolish","forbidden","force-fed","forever","forgiving","forgotten","formula","fortune","foul","frantic","free","freebie","freedom","frenzied","frenzy","frightening","frisky","frugal","frustrated","fulfill","fulfilled","full","fully","fun","fun-loving","fundamentals","funniest","funny","furious","gambling","gargantuan","genius","genuine","gift","gigantic","giveaway","glamorous","gleeful","glorious","glowing","goddamn","gorgeous","graceful","grateful","gratified","gravity","great","greatest","greatness","greed","greedy","gripping","grit","grounded","growth","guaranteed","guilt","guilt-free","gullible","guts","hack","happiness","happy","harmful","harsh","hate","have you heard","havoc","hazardous","healthy","heart","heartbreaking","heartwarming","heavenly","hell","helpful","helplessness","hero","hesitant","hidden","high tech","highest","highly effective","hilarious","hoak","hoax","honest","honored","hope","hopeful","horribly","horrific","horrifying","horror","hostile","how to","huge","humility","humor","hurricane","hurry","hypnotic","idiot","ignite","illegal","illusive","imagination","immediately","imminently","impatience","impatient","impenetrable","important","impressive","improved","in the zone","incapable","incapacitated","incompetent","inconsiderate","increase","incredible","indecisive","indulgence","indulgent","inexpensive","inferior","informative","infuriated","ingredients","innocent","innovative","insane","insecure","insider","insidious","inspired","inspiring","instant savings","instantly","instructive","insult","intel","intelligent","intense","interesting","intriguing","introducing","invasion","investment","iron-clad","ironclad","irresistible","irs","is here","jackpot","jail","jaw-dropping","jealous","jeopardy","jittery","jovial","joyous","jubilant","judgmental","jumpstart","just arrived","keen","kickass","kickstart","kill","killed","killing","kills","know it all","lame","largest","lascivious","last","last chance","last minute","latest","laugh","laughing","launch","launching","lavishly","lawsuit","lazy","left behind","legendary","legitimate","liberal","liberated","lick","lies","life-changing","lifetime","light","lighthearted","likely","limited","literally","little-known","loathsome","lonely","looming","loser","lost","love","lucrative","lunatic","lurking","lust","luxurious","luxury","lying","magic","magical","magnificent","mainstream","malicious","mammoth","manipulative","marked down","massive","master","masterclass","maul","mediocre","meditative","meltdown","memorability","memorable","menacing","mesmerizing","meticulous","mind-blowing","minimalist","miracle","mired","mischievous","misgiving","missing out","mistake","monetize","money","moneyback","moneygrubbing","monumental","most important","motivated","mouth-watering","murder","mystery","nail","naked","natural","naughty","nazi","nest egg","never","new","nightmare","no good","no obligation","no one talks about","no questions asked","no risk","no strings attached","non-controlling","noted","novelty","now","obnoxious","obsessed","obsession","obvious","odd","off-kilter","off-limits","off-the record","offensive","official","okay","on-demand","open-minded","opportunities","optimistic","ordeal","outlawed","outrageousness","outstanding","overcome","overjoyed","overnight","overwhelmed","packed","painful","painless","painstaking","pale","panic","panicked","paralyzed","pas","passionate","pathetic","pay zero","payback","perfect","peril","perplexed","perspective","pessimistic","pioneering","piranha","pitfall","pitiful","placid","plague","played","playful","pleased","pluck","plummet","plunge","poison","poisonous","polarizing","poor","popular","portfolio","pound","powerful","powerless","practical","preposterous","prestige","price","priceless","pride","prison","privacy","private","privileged","prize","problem","productive","professional","profit","profitable","profound","promiscuous","promising","promote","protect","protected","proven","provocative","provoke","psychological","pummel","punch","punish","pus","quadruple","quality","quarrelsome","quick","quick-start","quickly","quiet","radiant","rare","ravenous","rebellious","recession-proof","reckoning","recognized","recommend","recreate","reduced","reflective","refugee","refund","refundable","reject","relaxed","release","relentless","reliable","remarkable","replicate","report","reprimanding","repulsed","repulsive","research","resentful","resourceful","responsible","responsive","rested","restricted","results","retaliating","reveal","revealing","revenge","revengeful","revisited","revolting","revolutionary","reward","rich","ridiculous","risky","riveting","rookie","rowdy","ruin","rules","ruthless","sabotaging","sacred","sadistic","sadly","sadness","safe","safety","sale","sampler","sarcastic","satisfied","savage","savagery","save","savings","savvy","scam","scandal","scandalous","scarce","scared","scary","scornful","scream","searing","secret","secret agenda","secret plot","secrets","secure","security","seductive","seething","seize","selected","self-hating","self-sufficient","sensational","senseless","sensual","serene","seriously","severe","sex","sexy","shaking","shameful","shameless","shaming","shatter","shellacking","shocking","should","shrewd","sick and tired","signs","silly","simple","simplicity","simplified","simplistic","sincere","sinful","sins","six-figure","sizable","sizzle","sizzled","sizzles","sizzling","sizzlingly","skill","skyrocket","slaughter","slave","sleazy","sleeping","sly","smash","smiling","smug","smuggle","smuggled","sneak-peek","sneaky","sniveling","snob","snooty","snotty","soar","soaring","solid","solution","spank","special","spectacular","speedy","spell-binding","spine","spirit","spirited","spiteful","spoiler","spontaneous","spotlight","spunky","squirming","stable","staggering","startling","steady","steal","stealthy","steamy","step-by-step","still","stoic","stop","strange","strangle","strategy","stressed","strong","strongly suggest","struggle","stuck up","studies","stunning","stupid","stupid-simple","sturdy","sublime","succeed","success","successful","suck","suddenly","suffer","sunny","super","super-human","superb","supercharge","superior","supported","supportive","sure","sure fire","surefire","surge","surging","surprise","surprised","surprising","survival","survive","suspicious","sweaty","swoon","swoon-worthy","tailspin","tank","tantalizing","targeted","tawdry","tease","technology","teetering","tempting","tenacious","tense","terrible","terrific","terrified","terrifying","terror","terrorist","tested","thankful","the truth","threaten","threatened","thrilled","thrilling","thug","ticked off","tickled","timely","today","torture","toxic","track record","trade secret","tragedy","tragic","transform","transparency","trap","trapped","trauma","traumatized","treacherous","treasure","tremendous","trend","tricks","triggers","triple","triumph","truly","trusting","trustworthy","truth","truthful","turbo-charge","turbocharges","tweaks","twitching","ultimate","unadulterated","unassuming","unauthorized","unbelievable","unburdened","uncaring","uncensored","uncertain","uncomfortable","unconditional","uncontrollable","unconventional","uncovered","undeniable","under priced","undercover","underground","underhanded","underused","unexpected","unforgettable","unheard of","unhurried","uninterested","unique","unjustified","unknowingly","unleashed","unlimited","unlock","unparalleled","unpopular","unreliable","unresponsive","unseen","unstable","unstoppable","unsure","unsurpassed","untapped","unusual","up-sell","upbeat","uplifted","uplifting","urge","urgent","useful","useless","validate","valor","valuable","value","vanquish","vaporize","venomous","verify","vibrant","vicious","victim","victory","vigorous","vilified","vindictive","violated","violent","volatile","vulnerable","waiting","wanted","wanton","warning","waste","weak","wealth","weird","what no one tells you","whip","whopping","wicked","wild","willpower","withheld","wonderful","wondrous","woozy","world","worry","worst","worthwhile","wounded","wreaking","youthful","zen","zinger"],"diacritics":{"A":"[\\u0041\\u24B6\\uFF21\\u00C0\\u00C1\\u00C2\\u1EA6\\u1EA4\\u1EAA\\u1EA8\\u00C3\\u0100\\u0102\\u1EB0\\u1EAE\\u1EB4\\u1EB2\\u0226\\u01E0\\u00C4\\u01DE\\u1EA2\\u00C5\\u01FA\\u01CD\\u0200\\u0202\\u1EA0\\u1EAC\\u1EB6\\u1E00\\u0104\\u023A\\u2C6F]","AA":"[\\uA732]","AE":"[\\u00C6\\u01FC\\u01E2]","AO":"[\\uA734]","AU":"[\\uA736]","AV":"[\\uA738\\uA73A]","AY":"[\\uA73C]","B":"[\\u0042\\u24B7\\uFF22\\u1E02\\u1E04\\u1E06\\u0243\\u0182\\u0181]","C":"[\\u0043\\u24B8\\uFF23\\u0106\\u0108\\u010A\\u010C\\u00C7\\u1E08\\u0187\\u023B\\uA73E]","D":"[\\u0044\\u24B9\\uFF24\\u1E0A\\u010E\\u1E0C\\u1E10\\u1E12\\u1E0E\\u0110\\u018B\\u018A\\u0189\\uA779]","DZ":"[\\u01F1\\u01C4]","Dz":"[\\u01F2\\u01C5]","E":"[\\u0045\\u24BA\\uFF25\\u00C8\\u00C9\\u00CA\\u1EC0\\u1EBE\\u1EC4\\u1EC2\\u1EBC\\u0112\\u1E14\\u1E16\\u0114\\u0116\\u00CB\\u1EBA\\u011A\\u0204\\u0206\\u1EB8\\u1EC6\\u0228\\u1E1C\\u0118\\u1E18\\u1E1A\\u0190\\u018E]","F":"[\\u0046\\u24BB\\uFF26\\u1E1E\\u0191\\uA77B]","G":"[\\u0047\\u24BC\\uFF27\\u01F4\\u011C\\u1E20\\u011E\\u0120\\u01E6\\u0122\\u01E4\\u0193\\uA7A0\\uA77D\\uA77E]","H":"[\\u0048\\u24BD\\uFF28\\u0124\\u1E22\\u1E26\\u021E\\u1E24\\u1E28\\u1E2A\\u0126\\u2C67\\u2C75\\uA78D]","I":"[\\u0049\\u24BE\\uFF29\\u00CC\\u00CD\\u00CE\\u0128\\u012A\\u012C\\u0130\\u00CF\\u1E2E\\u1EC8\\u01CF\\u0208\\u020A\\u1ECA\\u012E\\u1E2C\\u0197]","J":"[\\u004A\\u24BF\\uFF2A\\u0134\\u0248]","K":"[\\u004B\\u24C0\\uFF2B\\u1E30\\u01E8\\u1E32\\u0136\\u1E34\\u0198\\u2C69\\uA740\\uA742\\uA744\\uA7A2]","L":"[\\u004C\\u24C1\\uFF2C\\u013F\\u0139\\u013D\\u1E36\\u1E38\\u013B\\u1E3C\\u1E3A\\u0141\\u023D\\u2C62\\u2C60\\uA748\\uA746\\uA780]","LJ":"[\\u01C7]","Lj":"[\\u01C8]","M":"[\\u004D\\u24C2\\uFF2D\\u1E3E\\u1E40\\u1E42\\u2C6E\\u019C]","N":"[\\u004E\\u24C3\\uFF2E\\u01F8\\u0143\\u00D1\\u1E44\\u0147\\u1E46\\u0145\\u1E4A\\u1E48\\u0220\\u019D\\uA790\\uA7A4]","NJ":"[\\u01CA]","Nj":"[\\u01CB]","O":"[\\u004F\\u24C4\\uFF2F\\u00D2\\u00D3\\u00D4\\u1ED2\\u1ED0\\u1ED6\\u1ED4\\u00D5\\u1E4C\\u022C\\u1E4E\\u014C\\u1E50\\u1E52\\u014E\\u022E\\u0230\\u00D6\\u022A\\u1ECE\\u0150\\u01D1\\u020C\\u020E\\u01A0\\u1EDC\\u1EDA\\u1EE0\\u1EDE\\u1EE2\\u1ECC\\u1ED8\\u01EA\\u01EC\\u00D8\\u01FE\\u0186\\u019F\\uA74A\\uA74C]","OI":"[\\u01A2]","OO":"[\\uA74E]","OU":"[\\u0222]","P":"[\\u0050\\u24C5\\uFF30\\u1E54\\u1E56\\u01A4\\u2C63\\uA750\\uA752\\uA754]","Q":"[\\u0051\\u24C6\\uFF31\\uA756\\uA758\\u024A]","R":"[\\u0052\\u24C7\\uFF32\\u0154\\u1E58\\u0158\\u0210\\u0212\\u1E5A\\u1E5C\\u0156\\u1E5E\\u024C\\u2C64\\uA75A\\uA7A6\\uA782]","S":"[\\u0053\\u24C8\\uFF33\\u1E9E\\u015A\\u1E64\\u015C\\u1E60\\u0160\\u1E66\\u1E62\\u1E68\\u0218\\u015E\\u2C7E\\uA7A8\\uA784]","T":"[\\u0054\\u24C9\\uFF34\\u1E6A\\u0164\\u1E6C\\u021A\\u0162\\u1E70\\u1E6E\\u0166\\u01AC\\u01AE\\u023E\\uA786]","TZ":"[\\uA728]","U":"[\\u0055\\u24CA\\uFF35\\u00D9\\u00DA\\u00DB\\u0168\\u1E78\\u016A\\u1E7A\\u016C\\u00DC\\u01DB\\u01D7\\u01D5\\u01D9\\u1EE6\\u016E\\u0170\\u01D3\\u0214\\u0216\\u01AF\\u1EEA\\u1EE8\\u1EEE\\u1EEC\\u1EF0\\u1EE4\\u1E72\\u0172\\u1E76\\u1E74\\u0244]","V":"[\\u0056\\u24CB\\uFF36\\u1E7C\\u1E7E\\u01B2\\uA75E\\u0245]","VY":"[\\uA760]","W":"[\\u0057\\u24CC\\uFF37\\u1E80\\u1E82\\u0174\\u1E86\\u1E84\\u1E88\\u2C72]","X":"[\\u0058\\u24CD\\uFF38\\u1E8A\\u1E8C]","Y":"[\\u0059\\u24CE\\uFF39\\u1EF2\\u00DD\\u0176\\u1EF8\\u0232\\u1E8E\\u0178\\u1EF6\\u1EF4\\u01B3\\u024E\\u1EFE]","Z":"[\\u005A\\u24CF\\uFF3A\\u0179\\u1E90\\u017B\\u017D\\u1E92\\u1E94\\u01B5\\u0224\\u2C7F\\u2C6B\\uA762]","a":"[\\u0061\\u24D0\\uFF41\\u1E9A\\u00E0\\u00E1\\u00E2\\u1EA7\\u1EA5\\u1EAB\\u1EA9\\u00E3\\u0101\\u0103\\u1EB1\\u1EAF\\u1EB5\\u1EB3\\u0227\\u01E1\\u00E4\\u01DF\\u1EA3\\u00E5\\u01FB\\u01CE\\u0201\\u0203\\u1EA1\\u1EAD\\u1EB7\\u1E01\\u0105\\u2C65\\u0250]","aa":"[\\uA733]","ae":"[\\u00E6\\u01FD\\u01E3]","ao":"[\\uA735]","au":"[\\uA737]","av":"[\\uA739\\uA73B]","ay":"[\\uA73D]","b":"[\\u0062\\u24D1\\uFF42\\u1E03\\u1E05\\u1E07\\u0180\\u0183\\u0253]","c":"[\\u0063\\u24D2\\uFF43\\u0107\\u0109\\u010B\\u010D\\u00E7\\u1E09\\u0188\\u023C\\uA73F\\u2184]","d":"[\\u0064\\u24D3\\uFF44\\u1E0B\\u010F\\u1E0D\\u1E11\\u1E13\\u1E0F\\u0111\\u018C\\u0256\\u0257\\uA77A]","dz":"[\\u01F3\\u01C6]","e":"[\\u0065\\u24D4\\uFF45\\u00E8\\u00E9\\u00EA\\u1EC1\\u1EBF\\u1EC5\\u1EC3\\u1EBD\\u0113\\u1E15\\u1E17\\u0115\\u0117\\u00EB\\u1EBB\\u011B\\u0205\\u0207\\u1EB9\\u1EC7\\u0229\\u1E1D\\u0119\\u1E19\\u1E1B\\u0247\\u025B\\u01DD]","f":"[\\u0066\\u24D5\\uFF46\\u1E1F\\u0192\\uA77C]","g":"[\\u0067\\u24D6\\uFF47\\u01F5\\u011D\\u1E21\\u011F\\u0121\\u01E7\\u0123\\u01E5\\u0260\\uA7A1\\u1D79\\uA77F]","h":"[\\u0068\\u24D7\\uFF48\\u0125\\u1E23\\u1E27\\u021F\\u1E25\\u1E29\\u1E2B\\u1E96\\u0127\\u2C68\\u2C76\\u0265]","hv":"[\\u0195]","i":"[\\u0069\\u24D8\\uFF49\\u00EC\\u00ED\\u00EE\\u0129\\u012B\\u012D\\u00EF\\u1E2F\\u1EC9\\u01D0\\u0209\\u020B\\u1ECB\\u012F\\u1E2D\\u0268\\u0131]","j":"[\\u006A\\u24D9\\uFF4A\\u0135\\u01F0\\u0249]","k":"[\\u006B\\u24DA\\uFF4B\\u1E31\\u01E9\\u1E33\\u0137\\u1E35\\u0199\\u2C6A\\uA741\\uA743\\uA745\\uA7A3]","l":"[\\u006C\\u24DB\\uFF4C\\u0140\\u013A\\u013E\\u1E37\\u1E39\\u013C\\u1E3D\\u1E3B\\u017F\\u0142\\u019A\\u026B\\u2C61\\uA749\\uA781\\uA747]","lj":"[\\u01C9]","m":"[\\u006D\\u24DC\\uFF4D\\u1E3F\\u1E41\\u1E43\\u0271\\u026F]","n":"[\\u006E\\u24DD\\uFF4E\\u01F9\\u0144\\u00F1\\u1E45\\u0148\\u1E47\\u0146\\u1E4B\\u1E49\\u019E\\u0272\\u0149\\uA791\\uA7A5]","nj":"[\\u01CC]","o":"[\\u006F\\u24DE\\uFF4F\\u00F2\\u00F3\\u00F4\\u1ED3\\u1ED1\\u1ED7\\u1ED5\\u00F5\\u1E4D\\u022D\\u1E4F\\u014D\\u1E51\\u1E53\\u014F\\u022F\\u0231\\u00F6\\u022B\\u1ECF\\u0151\\u01D2\\u020D\\u020F\\u01A1\\u1EDD\\u1EDB\\u1EE1\\u1EDF\\u1EE3\\u1ECD\\u1ED9\\u01EB\\u01ED\\u00F8\\u01FF\\u0254\\uA74B\\uA74D\\u0275]","oi":"[\\u01A3]","ou":"[\\u0223]","oo":"[\\uA74F]","p":"[\\u0070\\u24DF\\uFF50\\u1E55\\u1E57\\u01A5\\u1D7D\\uA751\\uA753\\uA755]","q":"[\\u0071\\u24E0\\uFF51\\u024B\\uA757\\uA759]","r":"[\\u0072\\u24E1\\uFF52\\u0155\\u1E59\\u0159\\u0211\\u0213\\u1E5B\\u1E5D\\u0157\\u1E5F\\u024D\\u027D\\uA75B\\uA7A7\\uA783]","s":"[\\u0073\\u24E2\\uFF53\\u015B\\u1E65\\u015D\\u1E61\\u0161\\u1E67\\u1E63\\u1E69\\u0219\\u015F\\u023F\\uA7A9\\uA785\\u1E9B]","ss":"[\\u00DF]","t":"[\\u0074\\u24E3\\uFF54\\u1E6B\\u1E97\\u0165\\u1E6D\\u021B\\u0163\\u1E71\\u1E6F\\u0167\\u01AD\\u0288\\u2C66\\uA787]","tz":"[\\uA729]","u":"[\\u0075\\u24E4\\uFF55\\u00F9\\u00FA\\u00FB\\u0169\\u1E79\\u016B\\u1E7B\\u016D\\u00FC\\u01DC\\u01D8\\u01D6\\u01DA\\u1EE7\\u016F\\u0171\\u01D4\\u0215\\u0217\\u01B0\\u1EEB\\u1EE9\\u1EEF\\u1EED\\u1EF1\\u1EE5\\u1E73\\u0173\\u1E77\\u1E75\\u0289]","v":"[\\u0076\\u24E5\\uFF56\\u1E7D\\u1E7F\\u028B\\uA75F\\u028C]","vy":"[\\uA761]","w":"[\\u0077\\u24E6\\uFF57\\u1E81\\u1E83\\u0175\\u1E87\\u1E85\\u1E98\\u1E89\\u2C73]","x":"[\\u0078\\u24E7\\uFF58\\u1E8B\\u1E8D]","y":"[\\u0079\\u24E8\\uFF59\\u1EF3\\u00FD\\u0177\\u1EF9\\u0233\\u1E8F\\u00FF\\u1EF7\\u1E99\\u1EF5\\u01B4\\u024F\\u1EFF]","z":"[\\u007A\\u24E9\\uFF5A\\u017A\\u1E91\\u017C\\u017E\\u1E93\\u1E95\\u01B6\\u0225\\u0240\\u2C6C\\uA763]"},"researchesTests":["contentHasTOC","contentHasShortParagraphs","contentHasAssets","keywordInTitle","keywordInMetaDescription","keywordInPermalink","keywordIn10Percent","keywordInContent","keywordInSubheadings","keywordInImageAlt","keywordDensity","keywordNotUsed","lengthContent","lengthPermalink","linksHasInternal","linksHasExternals","linksNotAllExternals","titleStartWithKeyword","titleSentiment","titleHasPowerWords","titleHasNumber","hasContentAI"],"hasRedirection":true,"hasBreadcrumb":false},"homeUrl":"http:\/\/loopitm.org.cn\/en","objectID":5408,"objectType":"post","locale":"en","localeFull":"en_GB","overlayImages":{"play":{"name":"Play icon","url":"http:\/\/loopitm.org.cn\/wp-content\/plugins\/seo-by-rank-math\/assets\/admin\/img\/icon-play.png","path":"\/www\/wwwroot\/loopitm.org.cn\/wp-content\/plugins\/seo-by-rank-math\/assets\/admin\/img\/icon-play.png","position":"middle_center"},"gif":{"name":"GIF icon","url":"http:\/\/loopitm.org.cn\/wp-content\/plugins\/seo-by-rank-math\/assets\/admin\/img\/icon-gif.png","path":"\/www\/wwwroot\/loopitm.org.cn\/wp-content\/plugins\/seo-by-rank-math\/assets\/admin\/img\/icon-gif.png","position":"middle_center"}},"defautOgImage":"http:\/\/loopitm.org.cn\/wp-content\/plugins\/seo-by-rank-math\/assets\/admin\/img\/social-placeholder.jpg","customPermalinks":true,"isUserRegistered":true,"autoSuggestKeywords":true,"connectSiteUrl":"https:\/\/rankmath.com\/auth?site=http%3A%2F%2Floopitm.org.cn%2Fen&r=http%3A%2F%2Floopitm.org.cn%2Fen%2Fwp-json%2Fwp%2Fv2%2Fpages%2F5408%3Fnonce%3D17491a186b&pro=1","maxTags":100,"trendsIcon":"<\/svg>","showScore":true,"siteFavIcon":"http:\/\/loopitm.org.cn\/wp-content\/uploads\/2024\/07\/1721283017-1721283017-1721283017-\u672a\u6807\u9898-2-05.png","canUser":{"general":false,"advanced":false,"snippet":false,"social":false,"analysis":false,"analytics":false,"content_ai":false},"showKeywordIntent":true,"isPro":true,"is_front_page":false,"trendsUpgradeLink":"https:\/\/rankmath.com\/pricing\/?utm_source=Plugin&utm_medium=CE%20General%20Tab%20Trends&utm_campaign=WP","trendsUpgradeLabel":"Upgrade","trendsPreviewImage":"http:\/\/loopitm.org.cn\/wp-content\/plugins\/seo-by-rank-math\/assets\/admin\/img\/trends-preview.jpg","currentEditor":false,"homepageData":{"assessor":{"powerWords":["a cut above","absolute","absolutely","absolutely lowest","absurd","abuse","accurate","accuse","achieve","actionable","adaptable","adequate","admit","adorable","advantage","advice","affordable","aggravate","aggressive","agitated","agonizing","agony","alarmed","alarming","alienated","aligned","alive","all-inclusive","alluring","always","amazing","amp","animated","annihilate","announcing","anonymous","antagonistic","anxious","apocalypse","appalled","approved","approving","argumentative","armageddon","arrogant","ass kicking","assault","assured","astonishing","astounded","astounding","at ease","atrocious","attack","attractive","audacity","authentic","authoritative","authority","avoid","aware","awe-inspiring","awesome","awkward","backbone","backdoor","backed","backlash","backstabbing","badass","balanced","banned","bargain","barrage","basic","battle","beaming","beat down","beating","beautiful","beauty","begging","behind the scenes","belief","belong","best","best-selling","better","beware","big","billion","black market","blacklisted","blast","blessed","blinded","blissful","blood","bloodbath","bloodcurdling","bloody","blunder","blushing","bold","bomb","bona","bona fide","bonanza","bonus","bootleg","bottom line","bountiful","brave","bravery","brazen","break","breaking","breakthrough","breathtaking","bright","brilliant","broke","brutal","budget","buffoon","bullshit","bully","bumbling","buy","cadaver","calm","cancel anytime","capable","captivate","captivating","carefree","case study","cash","cataclysmic","catapult","catastrophe","caution","censored","centered","certain","certainly","certified","challenge","charming","cheap","cheat","cheat-sheet","cheer","cheerful","child-like","clarity","classified","clear","clueless","collapse","colorful","colossal","comfortable","compare","competitive","complete","completely","completeness","comprehensive","compromise","compulsive","concealed","conclusive","condemning","condescending","confess","confession","confessions","confident","confidential","conquer","conscientious","constructive","content","contrary","controlling","controversial","convenient","convert","cool","cooperative","copy","corpse","corrupt","corrupting","courage","courageous","cover-up","covert","coward","cowardly","crammed","crave","crazy","create","creative","cringeworthy","cripple","crisis","critical","crooked","crush","crushing","damaging","danger","dangerous","daring","dazzling","dead","deadline","deadly","death","decadent","deceived","deceptive","deep","defiance","definitely","definitive","defying","dejected","delicious","delight","delighted","delightful","delirious","delivered","demoralizing","deplorable","depraved","desire","desperate","despicable","destiny","destroy","detailed","devastating","devoted","diagnosed","direct","dirty","disadvantages","disastrous","discount","discover","disdainful","disempowered","disgusted","disgusting","dishonest","disillusioned","disoriented","distracted","distraught","distressed","distrustful","divulge","document","dollar","dominate","doomed","double","doubtful","download","dreadful","dreamy","drive","drowning","dumb","dynamic","eager","earnest","easily","easy","economical","ecstatic","edge","effective","efficient","effortless","elated","eliminate","elite","embarrass","embarrassed","embarrassing","emergency","emerging","emphasize","empowered","enchant","encouraged","endorsed","energetic","energy","enormous","enraged","enthusiastic","envy","epic","epidemic","essential","ethical","euphoric","evil","exactly","exasperated","excellent","excited","excitement","exciting","exclusive","exclusivity","excruciating","exhilarated","expensive","expert","explode","exploit","explosive","exposed","exquisite","extra","extraordinary","extremely","exuberant","eye-opening","fail","fail-proof","failure","faith","famous","fantasy","fascinating","fatigued","faux","faux pas","fearless","feast","feeble","festive","fide","fierce","fight","final","fine","fired","first","first ever","flirt","fluid","focus","focused","fool","fooled","foolish","forbidden","force-fed","forever","forgiving","forgotten","formula","fortune","foul","frantic","free","freebie","freedom","frenzied","frenzy","frightening","frisky","frugal","frustrated","fulfill","fulfilled","full","fully","fun","fun-loving","fundamentals","funniest","funny","furious","gambling","gargantuan","genius","genuine","gift","gigantic","giveaway","glamorous","gleeful","glorious","glowing","goddamn","gorgeous","graceful","grateful","gratified","gravity","great","greatest","greatness","greed","greedy","gripping","grit","grounded","growth","guaranteed","guilt","guilt-free","gullible","guts","hack","happiness","happy","harmful","harsh","hate","have you heard","havoc","hazardous","healthy","heart","heartbreaking","heartwarming","heavenly","hell","helpful","helplessness","hero","hesitant","hidden","high tech","highest","highly effective","hilarious","hoak","hoax","honest","honored","hope","hopeful","horribly","horrific","horrifying","horror","hostile","how to","huge","humility","humor","hurricane","hurry","hypnotic","idiot","ignite","illegal","illusive","imagination","immediately","imminently","impatience","impatient","impenetrable","important","impressive","improved","in the zone","incapable","incapacitated","incompetent","inconsiderate","increase","incredible","indecisive","indulgence","indulgent","inexpensive","inferior","informative","infuriated","ingredients","innocent","innovative","insane","insecure","insider","insidious","inspired","inspiring","instant savings","instantly","instructive","insult","intel","intelligent","intense","interesting","intriguing","introducing","invasion","investment","iron-clad","ironclad","irresistible","irs","is here","jackpot","jail","jaw-dropping","jealous","jeopardy","jittery","jovial","joyous","jubilant","judgmental","jumpstart","just arrived","keen","kickass","kickstart","kill","killed","killing","kills","know it all","lame","largest","lascivious","last","last chance","last minute","latest","laugh","laughing","launch","launching","lavishly","lawsuit","lazy","left behind","legendary","legitimate","liberal","liberated","lick","lies","life-changing","lifetime","light","lighthearted","likely","limited","literally","little-known","loathsome","lonely","looming","loser","lost","love","lucrative","lunatic","lurking","lust","luxurious","luxury","lying","magic","magical","magnificent","mainstream","malicious","mammoth","manipulative","marked down","massive","master","masterclass","maul","mediocre","meditative","meltdown","memorability","memorable","menacing","mesmerizing","meticulous","mind-blowing","minimalist","miracle","mired","mischievous","misgiving","missing out","mistake","monetize","money","moneyback","moneygrubbing","monumental","most important","motivated","mouth-watering","murder","mystery","nail","naked","natural","naughty","nazi","nest egg","never","new","nightmare","no good","no obligation","no one talks about","no questions asked","no risk","no strings attached","non-controlling","noted","novelty","now","obnoxious","obsessed","obsession","obvious","odd","off-kilter","off-limits","off-the record","offensive","official","okay","on-demand","open-minded","opportunities","optimistic","ordeal","outlawed","outrageousness","outstanding","overcome","overjoyed","overnight","overwhelmed","packed","painful","painless","painstaking","pale","panic","panicked","paralyzed","pas","passionate","pathetic","pay zero","payback","perfect","peril","perplexed","perspective","pessimistic","pioneering","piranha","pitfall","pitiful","placid","plague","played","playful","pleased","pluck","plummet","plunge","poison","poisonous","polarizing","poor","popular","portfolio","pound","powerful","powerless","practical","preposterous","prestige","price","priceless","pride","prison","privacy","private","privileged","prize","problem","productive","professional","profit","profitable","profound","promiscuous","promising","promote","protect","protected","proven","provocative","provoke","psychological","pummel","punch","punish","pus","quadruple","quality","quarrelsome","quick","quick-start","quickly","quiet","radiant","rare","ravenous","rebellious","recession-proof","reckoning","recognized","recommend","recreate","reduced","reflective","refugee","refund","refundable","reject","relaxed","release","relentless","reliable","remarkable","replicate","report","reprimanding","repulsed","repulsive","research","resentful","resourceful","responsible","responsive","rested","restricted","results","retaliating","reveal","revealing","revenge","revengeful","revisited","revolting","revolutionary","reward","rich","ridiculous","risky","riveting","rookie","rowdy","ruin","rules","ruthless","sabotaging","sacred","sadistic","sadly","sadness","safe","safety","sale","sampler","sarcastic","satisfied","savage","savagery","save","savings","savvy","scam","scandal","scandalous","scarce","scared","scary","scornful","scream","searing","secret","secret agenda","secret plot","secrets","secure","security","seductive","seething","seize","selected","self-hating","self-sufficient","sensational","senseless","sensual","serene","seriously","severe","sex","sexy","shaking","shameful","shameless","shaming","shatter","shellacking","shocking","should","shrewd","sick and tired","signs","silly","simple","simplicity","simplified","simplistic","sincere","sinful","sins","six-figure","sizable","sizzle","sizzled","sizzles","sizzling","sizzlingly","skill","skyrocket","slaughter","slave","sleazy","sleeping","sly","smash","smiling","smug","smuggle","smuggled","sneak-peek","sneaky","sniveling","snob","snooty","snotty","soar","soaring","solid","solution","spank","special","spectacular","speedy","spell-binding","spine","spirit","spirited","spiteful","spoiler","spontaneous","spotlight","spunky","squirming","stable","staggering","startling","steady","steal","stealthy","steamy","step-by-step","still","stoic","stop","strange","strangle","strategy","stressed","strong","strongly suggest","struggle","stuck up","studies","stunning","stupid","stupid-simple","sturdy","sublime","succeed","success","successful","suck","suddenly","suffer","sunny","super","super-human","superb","supercharge","superior","supported","supportive","sure","sure fire","surefire","surge","surging","surprise","surprised","surprising","survival","survive","suspicious","sweaty","swoon","swoon-worthy","tailspin","tank","tantalizing","targeted","tawdry","tease","technology","teetering","tempting","tenacious","tense","terrible","terrific","terrified","terrifying","terror","terrorist","tested","thankful","the truth","threaten","threatened","thrilled","thrilling","thug","ticked off","tickled","timely","today","torture","toxic","track record","trade secret","tragedy","tragic","transform","transparency","trap","trapped","trauma","traumatized","treacherous","treasure","tremendous","trend","tricks","triggers","triple","triumph","truly","trusting","trustworthy","truth","truthful","turbo-charge","turbocharges","tweaks","twitching","ultimate","unadulterated","unassuming","unauthorized","unbelievable","unburdened","uncaring","uncensored","uncertain","uncomfortable","unconditional","uncontrollable","unconventional","uncovered","undeniable","under priced","undercover","underground","underhanded","underused","unexpected","unforgettable","unheard of","unhurried","uninterested","unique","unjustified","unknowingly","unleashed","unlimited","unlock","unparalleled","unpopular","unreliable","unresponsive","unseen","unstable","unstoppable","unsure","unsurpassed","untapped","unusual","up-sell","upbeat","uplifted","uplifting","urge","urgent","useful","useless","validate","valor","valuable","value","vanquish","vaporize","venomous","verify","vibrant","vicious","victim","victory","vigorous","vilified","vindictive","violated","violent","volatile","vulnerable","waiting","wanted","wanton","warning","waste","weak","wealth","weird","what no one tells you","whip","whopping","wicked","wild","willpower","withheld","wonderful","wondrous","woozy","world","worry","worst","worthwhile","wounded","wreaking","youthful","zen","zinger"],"diacritics":true,"researchesTests":["contentHasTOC","contentHasShortParagraphs","contentHasAssets","keywordInTitle","keywordInMetaDescription","keywordInPermalink","keywordIn10Percent","keywordInContent","keywordInSubheadings","keywordInImageAlt","keywordDensity","keywordNotUsed","lengthContent","lengthPermalink","linksHasInternal","linksHasExternals","linksNotAllExternals","titleStartWithKeyword","titleSentiment","titleHasPowerWords","titleHasNumber","hasContentAI"],"hasBreadcrumb":false,"serpData":{"title":"%sitename% %page% %sep% %sitedesc%","description":"","titleTemplate":"%sitename% %page% %sep% %sitedesc%","descriptionTemplate":"","focusKeywords":"","breadcrumbTitle":"Home","robots":{"index":true},"advancedRobots":{"max-snippet":"-1","max-video-preview":"-1","max-image-preview":"large"},"facebookTitle":"","facebookDescription":"","facebookImage":"","facebookImageID":""}}},"tocTitle":"Table of Contents","tocExcludeHeadings":[],"listStyle":"ul"},"_links":{"self":[{"href":"http:\/\/loopitm.org.cn\/en\/wp-json\/wp\/v2\/pages\/5408","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/loopitm.org.cn\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/loopitm.org.cn\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/loopitm.org.cn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/loopitm.org.cn\/en\/wp-json\/wp\/v2\/comments?post=5408"}],"version-history":[{"count":0,"href":"http:\/\/loopitm.org.cn\/en\/wp-json\/wp\/v2\/pages\/5408\/revisions"}],"wp:attachment":[{"href":"http:\/\/loopitm.org.cn\/en\/wp-json\/wp\/v2\/media?parent=5408"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}